Stephanie Healey | September 22, 2014
Three College of Science faculty are among the 23 recipients of Spring Core Pilot Grants from the Indiana Clinical and Translational Sciences Institute (CTSI). The Core Pilot Grant program provides small pilot grants to access labs and technology whose resources can help kick-start promising basic research projects with high potential to go on to attract additional dollars from outside funding sources, such as the National Institutes of Health and public foundations. The program provides all grant recipients access to more than 60 core facilities across the Indiana CTSI member institutions of Indiana University (IU), Purdue University and the University of Notre Dame.
Holly Goodson, professor of chemistry and biochemistry, received $10,000 to access the Genomics and Bioinformatics Core at Notre Dame in support of the project "Development of an improved chemical mutagenicity test based on a yeast continuous culture system." Given the large number of chemicals in the environment, food, and water, it is important to develop inexpensive and effective tests that can determine the potential harm of these compounds. The goal of this project is to develop a quantitative test to measure mutagenicity using the whole sequenced genome of yeast grown in continuous culture systems as the foundation of the test. This new test is designed to provide improved analysis of the long-term safety of complex mixtures of compounds at low levels, such as those found in reclaimed water.