Angela Cavalieri | Mar. 7, 2014 | Harper Cancer Research Institute
In the United States, about one out of eight women will develop invasive breast cancer over the course of her lifetime. Undergraduates working with Dr. Jenifer Prosperi’s lab seek to increase our understanding of underlying mechanisms of the process of breast cancer. Junior Science Pre-Professional major, Katia Fernandez, is currently studying the response of breast cancer cells to chemotherapy, focusing on the APC tumor suppressor.
"Chemotherapy resistance is a major problem in the management of patients with breast cancer, and many patients experience recurrence and ultimately die because of treatment failure. Emerging evidence suggest that some tumor cells can survive chemotherapy by activating the self-renewal pathways resulting in tumor proliferation and clinical recurrence," Fernandez said.