Nina Welding | May 26, 2019
One of the most complex and least understood organs in the human body is the brain. Playing a major role in every body system, the brain processes sensory information; regulates breathing, body temperature, and blood pressure; releases hormones; and so much more. But how it forms, specifically how physical and biological forces affect healthy growth and development of the brain, remains largely a mystery.
Since its inception, the Computational Mechanics of Morphology at Notre Dame (CoMMaND) lab has focused its activities on the brain, studying its form, development and function. Recently, the CoMMaND team received a National Science Foundation grant through the Computer Information Science and Engineering Research Initiation Initiative for $172,870 to continue its work modeling and analyzing cortical thicknesses as an indicator of healthy brain development.
The CoMMaND team will develop and use a novel open-source computational tool to analyze the cortical thickness of two large data sets of neuroimages containing more than 500 MRI scans. “This will allow us to generate a baseline for cortical thickness variations throughout the development of a healthy brain,” says Maria Holland, the Clare Boothe Luce Assistant Professor of Aerospace and Mechanical Engineering and CoMMaND director.
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