New research could provide new insights into tuberculosis and other diseases
Date: September 17, 2012•
Researchers Patricia A. Champion and Matthew Champion from the University of Notre Dame’s Eck Institute for Global Health have developed a method to directly detect bacterial protein secretion, which could provide new insights into a variety of diseases including tuberculosis.
The Champions point out that bacteria use a variety of secretion systems to transport proteins beyond their cell membranes in order to interact with their environment. For bacterial pathogens such as TB, these systems transport bacterial proteins that promote interaction with host cells, leading to virulent disease.